Research
| Title： | Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters |
|---|---|
| First author： | Li, Qingyuan; Cong, Rihao; Wang, Chaogang; Wang, Wei; Zhang, Guofan; Qi, Haigang; Li, Li |
| Journal： | SCIENTIFIC DATA |
| Years： | 2025 |
| DOI： | 10.1038/s41597-025-05822-y |
| Abstract： | This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F2 hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3 omega 3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying omega-3 fatty acid dynamics, enabling future investigations into sustainable marine resource utilization and climate resilience. |
